| 423 runs | v Somerset | Aigburth, Liverpool | 1911 | f8241 |
| 385 runs | v Somerset | Aigburth, Liverpool | 1908 | f7449 |
| 372 runs | v Worcestershire | War Memorial Ground, Amblecote | 1911 | f8265 |
| 370 runs | v Oxford University | The University Parks, Oxford | 1985 | f35773 |
| 361 runs | v Middlesex | Old Trafford, Manchester | 1994 | f41186 |
| 350 runs | v Durham | Riverside Ground, Chester-le-Street | 1998 | f43828 |
| 345 runs | v Durham | Riverside Ground, Chester-le-Street | 1996 | f42450 |
| 340 runs | v Cambridge Marylebone Cricket Club University | FP Fenner's Ground, Cambridge | 2017 | f57845 |
| 336 runs | v Somerset | Stanley Park, Blackpool | 2002 | f46738 |
| 312 runs | v Kent | Angel Ground, Tonbridge | 1909 | f7707 |
| 307 runs | v Sussex | Aigburth, Liverpool | 1907 | f7174 |
| 295 runs | v Surrey | Old Trafford, Manchester | 1949 | f18476 |
| 293 runs | v Warwickshire | Edgbaston, Birmingham | 1896 | f4457 |
| 292 runs | v Somerset | Recreation Ground, Bath | 1911 | f8408 |
| 292 runs | v Leicestershire | Old Trafford, Manchester | 1913 | f8811 |
| 289 runs | v Nottinghamshire | Trent Bridge, Nottingham | 1998 | f43862 |
| 286 runs | v Durham University Centre of Cricketing Excellence | The Racecourse, Durham | 2009 | f51550 |
| 284 runs | v Leicestershire | Aylestone Road, Leicester | 1921 | f9899 |
| 281 runs | v Sussex | Old Trafford, Manchester | 1906 | f6960 |
| 272 runs | v Essex | Old Trafford, Manchester | 1908 | f7507 |
| 270 runs | v Leicestershire | Bath Grounds, Ashby-de-la-Zouch | 1924 | f10906 |
| 269 runs | v Derbyshire | North Road, Glossop | 1899 | f5164 |
| 265 runs | v Hampshire | Old Trafford, Manchester | 1900 | f5284 |
| 263 runs | v Hampshire | Old Trafford, Manchester | 1994 | f41140 |
| 261 runs | v Derbyshire | Queen's Park, Chesterfield | 2025 | f63009 |
| 260 runs | v Somerset | County Ground, Taunton | 1898 | f4913 |
| 254 runs | v Nottinghamshire | Old Trafford, Manchester | 1898 | f4931 |
| 250 runs | v Derbyshire | The 3aaa County Ground, Derby | 2015 | f56353 |
| 248 runs | v Derbyshire | Old Trafford, Manchester | 1912 | f8667 |
| 248 runs | v Yorkshire | Aigburth, Liverpool | 1958 | f22446 |
| 246 runs | v Northamptonshire | County Ground, Northampton | 1911 | f8205 |
| 246 runs | v Glamorgan | St Helen's, Swansea | 1931 | f13433 |
| 244 runs | v Leicestershire | Grace Road, Leicester | 2015 | f56394 |
| 243 runs | v Gloucestershire | Ashley Down Ground, Bristol | 1894 | f4085 |
| 243 runs | v Warwickshire | Old Trafford, Manchester | 1901 | f5525 |
| 243 runs | v Middlesex | Old Trafford, Manchester | 1909 | f7812 |
| 240 runs | v Leicestershire | Grace Road, Leicester | 1984 | f35340 |
| 238 runs | v Leicestershire | Old Trafford, Manchester | 1908 | f7572 |
| 237 runs | v Gloucestershire | Old Trafford, Manchester | 1914 | f9205 |
| 234 runs | v Leicestershire | Grace Road, Leicester | 2005 | f48755 |
| 233 runs | v Worcestershire | Old Trafford, Manchester | 1978 | f32064 |
| 233 runs | v Northamptonshire | Old Trafford, Manchester | 1995 | f41821 |
| 232 runs | v Durham | Old Trafford, Manchester | 2008 | f50810 |
| 230 runs | v Somerset | Aigburth, Liverpool | 1893 | f3921 |
| 228 runs | v Gloucestershire | Ashley Down Ground, Bristol | 1911 | f8267 |
| 225 runs | v South Africans | Aigburth, Liverpool | 1912 | f8652 |
| 224 runs | v Derbyshire | North Road, Glossop | 1900 | f5424 |
| 222 runs | v Derbyshire | Queen's Park, Chesterfield | 1960 | f23255 |
| 222 runs | v Hampshire | Aigburth, Liverpool | 2011 | f53351 |
| 221 runs | v Oxford University | The University Parks, Oxford | 1888 | f3246 |
| 221 runs | v Cambridge University | Old Trafford, Manchester | 1962 | f24315 |
| 220 runs | v Glamorgan | Penrhyn Avenue, Rhos-on-Sea, Colwyn Bay | 1994 | f41150 |
| 219 runs | v Worcestershire | Old Trafford, Manchester | 2004 | f47971 |
| 218 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1989 | f38169 |
| 216 runs | v Surrey | Kennington Oval, Kennington | 1881 | f2437 |
| 216 runs | v Leicestershire | Old Trafford, Manchester | 1900 | f5482 |
| 208 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1924 | f10896 |
| 207 runs | v Nottinghamshire | Old Trafford, Manchester | 1905 | f6709 |
| 206 runs | v Glamorgan | Old Trafford, Manchester | 1982 | f34091 |
| 206 runs | v Northamptonshire | Emirates Old Trafford, Manchester | 2021 | f60387 |
| 204 runs | v Kent | Mote Park, Maidstone | 1882 | f2560 |
| 204 runs | v Warwickshire | Edgbaston, Birmingham | 1898 | f4904 |
| 201 runs | v Gloucestershire | Spa Ground, Gloucester | 1906 | f6905 |
| 201 runs | v Northamptonshire | County Ground, Northampton | 1975 | f30585 |
| 199 runs | v Leicestershire | Aylestone Road, Leicester | 1901 | f5571 |
| 197 runs | v Warwickshire | Old Trafford, Manchester | 1920 | f9651 |
| 192 runs | v Worcestershire | Old Trafford, Manchester | 1904 | f6438 |
| 192 runs | v Derbyshire | County Ground, Derby | 1999 | f44507 |
| 191 runs | v Nottinghamshire | Old Trafford, Manchester | 1877 | f2048 |
| 191 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1959 | f22652 |
| 189 runs | v Kent | Mote Park, Maidstone | 1929 | f12827 |
| 189 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1961 | f23744 |
| 188 runs | v Essex | County Ground, Leyton | 1920 | f9754 |
| 188 runs | v Gloucestershire | Aigburth, Liverpool | 1961 | f23806 |
| 188 runs | v Warwickshire | Edgbaston, Birmingham | 1968 | f27368 |
| 185 runs | v Derbyshire | The Park, Buxton | 1932 | f13935 |
| 184 runs | v Kent | Old Trafford, Manchester | 1901 | f5555 |
| 184 runs | v Yorkshire | North Marine Road, Scarborough | 1989 | f38290 |
| 184 runs | v Kent | Emirates Old Trafford, Manchester | 2022 | f60932 |
| 181 runs | v Yorkshire | Old Trafford, Manchester | 1989 | f38255 |
| 180 runs | v Gloucestershire | Victoria Ground, Cheltenham | 1925 | f11276 |
| 180 runs | v Leicestershire | Seedhill, Nelson | 1930 | f13081 |
| 179 runs | v Yorkshire | Old Trafford, Manchester | 1959 | f22673 |
| 178 runs | v Derbyshire | Aigburth, Liverpool | 2020 | f60208 |
| 177 runs | v Leicestershire | Old Trafford, Manchester | 1895 | f4225 |
| 176 runs | v Hampshire | County Ground, Southampton | 1900 | f5326 |
| 176 runs | v Hampshire | Old Trafford, Manchester | 1910 | f7978 |
| 176 runs | v Warwickshire | Seedhill, Nelson | 1928 | f12277 |
| 175 runs | v Gloucestershire | Ashley Down Ground, Bristol | 1893 | f3912 |
| 175 runs | v Nottinghamshire | Aigburth, Liverpool | 1950 | f18834 |
| 174 runs | v Essex | Stanley Park, Blackpool | 1930 | f13308 |
| 174 runs | v Oxford University | Old Trafford, Manchester | 1961 | f23777 |
| 173 runs | v Sussex | Old Trafford, Manchester | 1974 | f30187 |
| 171 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1908 | f7384 |
| 171 runs | v Glamorgan | Cardiff Arms Park, Cardiff | 1930 | f13063 |
| 171 runs | v Leicestershire | Old Trafford, Manchester | 1933 | f14419 |
| 171 runs | v Hampshire | County Ground, Southampton | 1960 | f23147 |
| 170 runs | v Leicestershire | Grace Road, Leicester | 1959 | f22883 |
| 170 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 2000 | f45071 |
| 168 runs | v Somerset | Emirates Old Trafford, Manchester | 2024 | f62353 |
| 167 runs | v Kent | Old Trafford, Manchester | 1955 | f20871 |
| 164 runs | v Somerset | Emirates Old Trafford, Manchester | 2017 | f57881 |
| 163 runs | v Northamptonshire | Trafalgar Road, Southport | 1971 | f28794 |
| 162 runs | v Warwickshire | Aigburth, Liverpool | 1956 | f21306 |
| 161 runs | v Derbyshire | County Ground, Derby | 1905 | f6566 |
| 161 runs | v Hampshire | Old Trafford, Manchester | 1998 | f43866 |
| 159 runs | v Worcestershire | Old Trafford, Manchester | 1902 | f5822 |
| 159 runs | v Kent | Old Trafford, Manchester | 1951 | f19112 |
| 154 runs | v Sussex | Old Trafford, Manchester | 1885 | f2923 |
| 154 runs | v Kent | Old Trafford, Manchester | 2000 | f45240 |
| 153 runs | v Warwickshire | Edgbaston, Birmingham | 1950 | f18679 |
| 153 runs | v Yorkshire | Headingley, Leeds | 1956 | f21285 |
| 151 runs | v Oxford University | The University Parks, Oxford | 1883 | f2616 |
| 150 runs | v Derbyshire | Queen's Park, Chesterfield | 1909 | f7818 |
| 147 runs | v Surrey | Kennington Oval, Kennington | 1887 | f3180 |
| 147 runs | v Warwickshire | Edgbaston, Birmingham | 2011 | f53215 |
| 146 runs | v Warwickshire | Trafalgar Road, Southport | 1962 | f24391 |
| 146 runs | v Hampshire | United Services Ground, Portsmouth | 1980 | f33160 |
| 145 runs | v Yorkshire | Bramall Lane, Sheffield | 1895 | f4236 |
| 141 runs | v Oxford University | Christ Church Ground, Oxford | 1906 | f6841 |
| 141 runs | v Durham | Riverside Ground, Chester-le-Street | 2000 | f45103 |
| 140 runs | v Yorkshire | Old Trafford, Manchester | 1919 | f9363 |
| 140 runs | v Sussex | Old Trafford, Manchester | 1924 | f10915 |
| 138 runs | v Glamorgan | St Helen's, Swansea | 1925 | f11228 |
| 138 runs | v Leicestershire | Aigburth, Liverpool | 1926 | f11521 |
| 138 runs | v Gloucestershire | Aigburth, Liverpool | 1926 | f11591 |
| 138 runs | v Nottinghamshire | Old Trafford, Manchester | 1978 | f32141 |
| 136 runs | v Kent | Old Trafford, Manchester | 1880 | f2291 |
| 135 runs | v Derbyshire | Old Trafford, Manchester | 1934 | f14748 |
| 135 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1946 | f17069 |
| 134 runs | v Sussex | Old Trafford, Manchester | 1956 | f21402 |
| 134 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1964 | f25281 |
| 133 runs | v Oxford University | The University Parks, Oxford | 1962 | f24224 |
| 132 runs | v Leicestershire | Old Trafford, Manchester | 1932 | f13980 |
| 131 runs | v Derbyshire | Old Trafford, Manchester | 1904 | f6493 |
| 131 runs | v Essex | Aigburth, Liverpool | 1910 | f7937 |
| 131 runs | v Northamptonshire | Town Ground, Rushden | 1963 | f24735 |
| 130 runs | v Sussex | Old Trafford, Manchester | 1947 | f17502 |
| 129 runs | v Leicestershire | Old Trafford, Manchester | 1920 | f9560 |
| 129 runs | v Derbyshire | Queen's Park, Chesterfield | 1955 | f20936 |
| 128 runs | v Derbyshire | North Road, Glossop | 1910 | f7921 |
| 128 runs | v Glamorgan | Aigburth, Liverpool | 1924 | f10817 |
| 128 runs | v Hampshire | May's Bounty, Basingstoke | 1991 | f39356 |
| 128 runs | v Durham | Riverside Ground, Chester-le-Street | 2006 | f49348 |
| 126 runs | v Northamptonshire | Town Ground, Kettering | 1926 | f11558 |
| 125 runs | v Gloucestershire | College Ground, Cheltenham | 1921 | f10057 |
| 125 runs | v Kent | Bat and Ball Ground, Gravesend | 1923 | f10520 |
| 125 runs | v Essex | Hoffman's Sports and Social Club Ground, Chelmsford | 1959 | f22938 |
| 124 runs | v Derbyshire | Trafalgar Road, Southport | 1968 | f27356 |
| 123 runs | v Surrey | The Kia Oval, Kennington | 2023 | f61611 |
| 122 runs | v Leicestershire | Grace Road, Leicester | 1960 | f23195 |
| 122 runs | v Hampshire | Trafalgar Road, Southport | 2013 | f54938 |
| 121 runs | v Warwickshire | Old Trafford, Manchester | 2010 | f52381 |
| 121 runs | v Kent | St Lawrence Ground, Canterbury | 2010 | f52534 |
| 119 runs | v Essex | County Ground, Leyton | 1903 | f6210 |
| 118 runs | v Essex | Old Trafford, Manchester | 1999 | f44462 |
| 117 runs | v Oxford University | Aigburth, Liverpool | 1887 | f3139 |
| 117 runs | v Somerset | Recreation Ground, Bath | 1954 | f20491 |
| 117 runs | v Worcestershire | Old Trafford, Manchester | 1987 | f36994 |
| 116 runs | v Gloucestershire | Aigburth, Liverpool | 1888 | f3297 |
| 115 runs | v Leicestershire | Grace Road, Leicester | 1991 | f39378 |
| 113 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1938 | f16100 |
| 112 runs | v Sussex | Old Trafford, Manchester | 1892 | f3712 |
| 111 runs | v Gloucestershire | Old Trafford, Manchester | 1935 | f15067 |
| 111 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1959 | f22802 |
| 111 runs | v Derbyshire | County Ground, Derby | 1993 | f40566 |
| 111 runs | v Hampshire | The Rose Bowl, Southampton | 2002 | f46704 |
| 109 runs | v Somerset | Old Trafford, Manchester | 1949 | f18250 |
| 109 runs | v Derbyshire | Old Trafford, Manchester | 1961 | f23737 |
| 108 runs | v Gloucestershire | Spa Ground, Gloucester | 1901 | f5601 |
| 108 runs | v Leicestershire | Aylestone Road, Leicester | 1903 | f6042 |
| 108 runs | v Nottinghamshire | Trent Bridge, Nottingham | 1926 | f11568 |
| 108 runs | v Nottinghamshire | Old Trafford, Manchester | 1965 | f25848 |
| 107 runs | v Kent | Angel Ground, Tonbridge | 1904 | f6374 |
| 107 runs | v Oxford University | The University Parks, Oxford | 1923 | f10467 |
| 107 runs | v Combined Services | Old Trafford, Manchester | 1955 | f21087 |
| 106 runs | v Surrey | Kennington Oval, Kennington | 1873 | f1764 |
| 106 runs | v Glamorgan | Old Trafford, Manchester | 1925 | f11325 |
| 104 runs | v Sussex | Old Trafford, Manchester | 1869 | f1537 |
| 104 runs | v Middlesex | Emirates Old Trafford, Manchester | 2019 | f59601 |
| 103 runs | v Derbyshire | County Ground, Derby | 1906 | f6843 |
| 103 runs | v Gloucestershire | Old Trafford, Manchester | 1934 | f14719 |
| 103 runs | v Glamorgan | St Helen's, Swansea | 1971 | f28683 |
| 102 runs | v Kent | Old Trafford, Manchester | 1937 | f15912 |
| 101 runs | v Kent | Crabble Athletic Ground, Dover | 1930 | f13285 |
| 101 runs | v Nottinghamshire | Trent Bridge, Nottingham | 1934 | f14620 |
| 99 runs | v Somerset | Clarence Park, Weston-super-Mare | 1976 | f31205 |
| 98 runs | v Essex | Old Trafford, Manchester | 1964 | f25333 |
| 98 runs | v Worcestershire | Stanley Park, Blackpool | 2011 | f53324 |
| 97 runs | v Worcestershire | Aigburth, Liverpool | 1905 | f6574 |
| 97 runs | v Oxford University | The University Parks, Oxford | 1922 | f10234 |
| 97 runs | v Derbyshire | Seedhill, Nelson | 1925 | f11377 |
| 97 runs | v Hampshire | Dean Park, Bournemouth | 1926 | f11741 |
| 97 runs | v Surrey | Old Trafford, Manchester | 1989 | f38265 |
| 96 runs | v Derbyshire | Old Trafford, Manchester | 1900 | f5289 |
| 96 runs | v Surrey | The Foster's Oval, Kennington | 1993 | f40540 |
| 95 runs | v Derbyshire | County Ground, Derby | 1876 | f1966 |
| 95 runs | v Nottinghamshire | Aigburth, Liverpool | 1920 | f9724 |
| 95 runs | v Northamptonshire | County Ground, Northampton | 1939 | f16708 |
| 95 runs | v Hampshire | Old Trafford, Manchester | 1957 | f21949 |
| 94 runs | v Middlesex | Old Trafford, Manchester | 1950 | f18843 |
| 93 runs | v Somerset | Old Trafford, Manchester | 1909 | f7843 |
| 91 runs | v Gloucestershire | County Ground, Bristol | 2015 | f56422 |
| 89 runs | v Essex | County Ground, Chelmsford | 1987 | f37187 |
| 87 runs | v Kent | St Lawrence Ground, Canterbury | 1907 | f7265 |
| 86 runs | v Combined Services | Old Trafford, Manchester | 1958 | f22327 |
| 86 runs | v Surrey | Church Road, Lytham St Annes | 1992 | f40071 |
| 85 runs | v Hampshire | United Services Ground, Portsmouth | 1925 | f11188 |
| 85 runs | v Sussex | Aigburth, Liverpool | 1964 | f25361 |
| 84 runs | v Nottinghamshire | Old Trafford, Manchester | 1899 | f5188 |
| 84 runs | v Leicestershire | Kirkby Road, Barwell | 1946 | f17156 |
| 84 runs | v Nottinghamshire | Old Trafford, Manchester | 1947 | f17700 |
| 84 runs | v Somerset | County Ground, Taunton | 1949 | f18417 |
| 83 runs | v Middlesex | Old Trafford, Manchester | 1911 | f8389 |
| 83 runs | v Derbyshire | Old Trafford, Manchester | 1952 | f19580 |
| 83 runs | v Sussex | County Ground, Hove | 1954 | f20668 |
| 82 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1950 | f18719 |
| 82 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1974 | f30149 |
| 80 runs | v Wales | Stanley Park, Blackpool | 1928 | f12521 |
| 80 runs | v Warwickshire | Old Trafford, Manchester | 1958 | f22336 |
| 79 runs | v Hampshire | Old Trafford, Manchester | 1959 | f22682 |
| 76 runs | v Surrey | Old Trafford, Manchester | 1907 | f7161 |
| 76 runs | v Worcestershire | County Ground, New Road, Worcester | 2005 | f48651 |
| 75 runs | v Kent | Angel Ground, Tonbridge | 1895 | f4261 |
| 75 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1923 | f10527 |
| 75 runs | v Kent | St Lawrence Ground, Canterbury | 2003 | f47303 |
| 74 runs | v Gloucestershire | Stanley Park, Blackpool | 1956 | f21438 |
| 74 runs | v Gloucestershire | The Royal and Sun Alliance County Ground, Bristol | 1985 | f35726 |
| 73 runs | v Derbyshire | Old Trafford, Manchester | 1878 | f2117 |
| 72 runs | v Derbyshire | Old Trafford, Manchester | 1932 | f13784 |
| 72 runs | v Warwickshire | Old Trafford, Manchester | 1955 | f20838 |
| 72 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1957 | f21826 |
| 72 runs | v Northamptonshire | County Ground, Northampton | 1979 | f32646 |
| 72 runs | v Glamorgan | St Helen's, Swansea | 1988 | f37582 |
| 71 runs | v Hampshire | County Ground, Southampton | 1899 | f5121 |
| 71 runs | v Scotland | Whitehaugh Oval, Paisley | 1956 | f21413 |
| 70 runs | v Kent | Old Trafford, Manchester | 1883 | f2619 |
| 70 runs | v Surrey | Kennington Oval, Kennington | 1904 | f6383 |
| 70 runs | v Kent | Aigburth, Liverpool | 2008 | f50960 |
| 68 runs | v Nottinghamshire | Old Trafford, Manchester | 1890 | f3560 |
| 68 runs | v Middlesex | Old Trafford, Manchester | 1893 | f3919 |
| 68 runs | v Warwickshire | Edgbaston, Birmingham | 1959 | f22914 |
| 66 runs | v Essex | Old Trafford, Manchester | 1897 | f4717 |
| 66 runs | v Gloucestershire | Old Trafford, Manchester | 1898 | f4963 |
| 66 runs | v Glamorgan | Sophia Gardens, Cardiff | 1981 | f33678 |
| 66 runs | v Worcestershire | County Ground, New Road, Worcester | 1989 | f38066 |
| 65 runs | v Derbyshire | County Ground, Derby | 1880 | f2330 |
| 65 runs | v Derbyshire | County Ground, Derby | 1898 | f4869 |
| 65 runs | v Warwickshire | Edgbaston, Birmingham | 2010 | f52435 |
| 64 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1900 | f5319 |
| 64 runs | v Sussex | County Ground, Hove | 1935 | f14946 |
| 64 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1947 | f17731 |
| 63 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1931 | f13480 |
| 63 runs | v Sussex | Old Trafford, Manchester | 1961 | f23954 |
| 62 runs | v Middlesex | Old Trafford, Manchester | 1865 | f1333 |
| 62 runs | v Derbyshire | County Ground, Derby | 1871 | f1662 |
| 62 runs | v Glamorgan | St Helen's, Swansea | 1973 | f29672 |
| 62 runs | v Warwickshire | Old Trafford, Manchester | 1989 | f38078 |
| 61 runs | v Northamptonshire | County Ground, Northampton | 1925 | f11341 |
| 60 runs | v Surrey | Kennington Oval, Kennington | 1880 | f2342 |
| 60 runs | v Nottinghamshire | Aigburth, Liverpool | 1906 | f6856 |
| 60 runs | v Kent | Old Trafford, Manchester | 1957 | f21697 |
| 60 runs | v Gloucestershire | Recreational Trust Ground, Lydney | 1966 | f26332 |
| 60 runs | v Derbyshire | County Ground, Derby | 1990 | f38697 |
| 60 runs | v Sussex | Church Road, Lytham St Annes | 1995 | f41850 |
| 60 runs | v Northamptonshire | County Ground, Northampton | 2014 | f55615 |
| 60 runs | v Durham | Stanley Park, Blackpool | 2024 | f62263 |
| 59 runs | v Marylebone Cricket Club | Lord's Cricket Ground, St John's Wood | 1878 | f2101 |
| 59 runs | v Yorkshire | Bramall Lane, Sheffield | 1899 | f5144 |
| 59 runs | v Kent | Old Trafford, Manchester | 1991 | f39386 |
| 59 runs | v Yorkshire | Headingley, Leeds | 1998 | f43827 |
| 58 runs | v Nottinghamshire | Old Trafford, Manchester | 1946 | f17171 |
| 55 runs | v Gloucestershire | College Ground, Cheltenham | 1961 | f23936 |
| 54 runs | v Derbyshire | Recreation Ground, Long Eaton | 1887 | f3158 |
| 54 runs | v Gloucestershire | Old Trafford, Manchester | 1913 | f8909 |
| 54 runs | v Sussex | Cricket Field Road, Horsham | 1983 | f34660 |
| 54 runs | v Sussex | Church Road, Lytham St Annes | 1987 | f37142 |
| 51 runs | v Nottinghamshire | Trent Bridge, Nottingham | 1988 | f37511 |
| 50 runs | v Yorkshire | Bramall Lane, Sheffield | 1881 | f2408 |
| 50 runs | v Oxford University | The University Parks, Oxford | 1885 | f2865 |