| 423 runs | v Somerset | Aigburth, Liverpool | 1911 | f8245 |
| 385 runs | v Somerset | Aigburth, Liverpool | 1908 | f7453 |
| 372 runs | v Worcestershire | War Memorial Ground, Amblecote | 1911 | f8269 |
| 370 runs | v Oxford University | The University Parks, Oxford | 1985 | f35777 |
| 361 runs | v Middlesex | Old Trafford, Manchester | 1994 | f41190 |
| 350 runs | v Durham | Riverside Ground, Chester-le-Street | 1998 | f43832 |
| 345 runs | v Durham | Riverside Ground, Chester-le-Street | 1996 | f42454 |
| 340 runs | v Cambridge Marylebone Cricket Club University | FP Fenner's Ground, Cambridge | 2017 | f57849 |
| 336 runs | v Somerset | Stanley Park, Blackpool | 2002 | f46742 |
| 312 runs | v Kent | Angel Ground, Tonbridge | 1909 | f7711 |
| 307 runs | v Sussex | Aigburth, Liverpool | 1907 | f7178 |
| 295 runs | v Surrey | Old Trafford, Manchester | 1949 | f18480 |
| 293 runs | v Warwickshire | Edgbaston, Birmingham | 1896 | f4459 |
| 292 runs | v Somerset | Recreation Ground, Bath | 1911 | f8412 |
| 292 runs | v Leicestershire | Old Trafford, Manchester | 1913 | f8815 |
| 289 runs | v Nottinghamshire | Trent Bridge, Nottingham | 1998 | f43866 |
| 286 runs | v Durham University Centre of Cricketing Excellence | The Racecourse, Durham | 2009 | f51554 |
| 284 runs | v Leicestershire | Aylestone Road, Leicester | 1921 | f9903 |
| 281 runs | v Sussex | Old Trafford, Manchester | 1906 | f6962 |
| 272 runs | v Essex | Old Trafford, Manchester | 1908 | f7511 |
| 270 runs | v Leicestershire | Bath Grounds, Ashby-de-la-Zouch | 1924 | f10910 |
| 269 runs | v Derbyshire | North Road, Glossop | 1899 | f5166 |
| 265 runs | v Hampshire | Old Trafford, Manchester | 1900 | f5286 |
| 263 runs | v Hampshire | Old Trafford, Manchester | 1994 | f41144 |
| 261 runs | v Derbyshire | Queen's Park, Chesterfield | 2025 | f63013 |
| 260 runs | v Somerset | County Ground, Taunton | 1898 | f4915 |
| 254 runs | v Nottinghamshire | Old Trafford, Manchester | 1898 | f4933 |
| 250 runs | v Derbyshire | The 3aaa County Ground, Derby | 2015 | f56357 |
| 248 runs | v Derbyshire | Old Trafford, Manchester | 1912 | f8671 |
| 248 runs | v Yorkshire | Aigburth, Liverpool | 1958 | f22450 |
| 246 runs | v Northamptonshire | County Ground, Northampton | 1911 | f8209 |
| 246 runs | v Glamorgan | St Helen's, Swansea | 1931 | f13437 |
| 244 runs | v Leicestershire | Grace Road, Leicester | 2015 | f56398 |
| 243 runs | v Gloucestershire | Ashley Down Ground, Bristol | 1894 | f4087 |
| 243 runs | v Warwickshire | Old Trafford, Manchester | 1901 | f5527 |
| 243 runs | v Middlesex | Old Trafford, Manchester | 1909 | f7816 |
| 240 runs | v Leicestershire | Grace Road, Leicester | 1984 | f35344 |
| 238 runs | v Leicestershire | Old Trafford, Manchester | 1908 | f7576 |
| 237 runs | v Gloucestershire | Old Trafford, Manchester | 1914 | f9209 |
| 234 runs | v Leicestershire | Grace Road, Leicester | 2005 | f48759 |
| 233 runs | v Worcestershire | Old Trafford, Manchester | 1978 | f32068 |
| 233 runs | v Northamptonshire | Old Trafford, Manchester | 1995 | f41825 |
| 232 runs | v Durham | Old Trafford, Manchester | 2008 | f50814 |
| 230 runs | v Somerset | Aigburth, Liverpool | 1893 | f3923 |
| 228 runs | v Gloucestershire | Ashley Down Ground, Bristol | 1911 | f8271 |
| 225 runs | v South Africans | Aigburth, Liverpool | 1912 | f8656 |
| 224 runs | v Derbyshire | North Road, Glossop | 1900 | f5426 |
| 222 runs | v Derbyshire | Queen's Park, Chesterfield | 1960 | f23259 |
| 222 runs | v Hampshire | Aigburth, Liverpool | 2011 | f53355 |
| 221 runs | v Oxford University | The University Parks, Oxford | 1888 | f3248 |
| 221 runs | v Cambridge University | Old Trafford, Manchester | 1962 | f24319 |
| 220 runs | v Glamorgan | Penrhyn Avenue, Rhos-on-Sea, Colwyn Bay | 1994 | f41154 |
| 219 runs | v Worcestershire | Old Trafford, Manchester | 2004 | f47975 |
| 218 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1989 | f38173 |
| 216 runs | v Surrey | Kennington Oval, Kennington | 1881 | f2439 |
| 216 runs | v Leicestershire | Old Trafford, Manchester | 1900 | f5484 |
| 208 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1924 | f10900 |
| 207 runs | v Nottinghamshire | Old Trafford, Manchester | 1905 | f6711 |
| 206 runs | v Glamorgan | Old Trafford, Manchester | 1982 | f34095 |
| 206 runs | v Northamptonshire | Emirates Old Trafford, Manchester | 2021 | f60391 |
| 204 runs | v Kent | Mote Park, Maidstone | 1882 | f2562 |
| 204 runs | v Warwickshire | Edgbaston, Birmingham | 1898 | f4906 |
| 201 runs | v Gloucestershire | Spa Ground, Gloucester | 1906 | f6907 |
| 201 runs | v Northamptonshire | County Ground, Northampton | 1975 | f30589 |
| 199 runs | v Leicestershire | Aylestone Road, Leicester | 1901 | f5573 |
| 197 runs | v Warwickshire | Old Trafford, Manchester | 1920 | f9655 |
| 192 runs | v Worcestershire | Old Trafford, Manchester | 1904 | f6440 |
| 192 runs | v Derbyshire | County Ground, Derby | 1999 | f44511 |
| 191 runs | v Nottinghamshire | Old Trafford, Manchester | 1877 | f2050 |
| 191 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1959 | f22656 |
| 189 runs | v Kent | Mote Park, Maidstone | 1929 | f12831 |
| 189 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1961 | f23748 |
| 188 runs | v Essex | County Ground, Leyton | 1920 | f9758 |
| 188 runs | v Gloucestershire | Aigburth, Liverpool | 1961 | f23810 |
| 188 runs | v Warwickshire | Edgbaston, Birmingham | 1968 | f27372 |
| 185 runs | v Derbyshire | The Park, Buxton | 1932 | f13939 |
| 184 runs | v Kent | Old Trafford, Manchester | 1901 | f5557 |
| 184 runs | v Yorkshire | North Marine Road, Scarborough | 1989 | f38294 |
| 184 runs | v Kent | Emirates Old Trafford, Manchester | 2022 | f60936 |
| 181 runs | v Yorkshire | Old Trafford, Manchester | 1989 | f38259 |
| 180 runs | v Gloucestershire | Victoria Ground, Cheltenham | 1925 | f11280 |
| 180 runs | v Leicestershire | Seedhill, Nelson | 1930 | f13085 |
| 179 runs | v Yorkshire | Old Trafford, Manchester | 1959 | f22677 |
| 178 runs | v Derbyshire | Aigburth, Liverpool | 2020 | f60212 |
| 177 runs | v Leicestershire | Old Trafford, Manchester | 1895 | f4227 |
| 176 runs | v Hampshire | County Ground, Southampton | 1900 | f5328 |
| 176 runs | v Hampshire | Old Trafford, Manchester | 1910 | f7982 |
| 176 runs | v Warwickshire | Seedhill, Nelson | 1928 | f12281 |
| 175 runs | v Gloucestershire | Ashley Down Ground, Bristol | 1893 | f3914 |
| 175 runs | v Nottinghamshire | Aigburth, Liverpool | 1950 | f18838 |
| 174 runs | v Essex | Stanley Park, Blackpool | 1930 | f13312 |
| 174 runs | v Oxford University | Old Trafford, Manchester | 1961 | f23781 |
| 173 runs | v Sussex | Old Trafford, Manchester | 1974 | f30191 |
| 171 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1908 | f7388 |
| 171 runs | v Glamorgan | Cardiff Arms Park, Cardiff | 1930 | f13067 |
| 171 runs | v Leicestershire | Old Trafford, Manchester | 1933 | f14423 |
| 171 runs | v Hampshire | County Ground, Southampton | 1960 | f23151 |
| 170 runs | v Leicestershire | Grace Road, Leicester | 1959 | f22887 |
| 170 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 2000 | f45075 |
| 168 runs | v Somerset | Emirates Old Trafford, Manchester | 2024 | f62357 |
| 167 runs | v Kent | Old Trafford, Manchester | 1955 | f20875 |
| 164 runs | v Somerset | Emirates Old Trafford, Manchester | 2017 | f57885 |
| 163 runs | v Northamptonshire | Trafalgar Road, Southport | 1971 | f28798 |
| 162 runs | v Warwickshire | Aigburth, Liverpool | 1956 | f21310 |
| 161 runs | v Derbyshire | County Ground, Derby | 1905 | f6568 |
| 161 runs | v Hampshire | Old Trafford, Manchester | 1998 | f43870 |
| 159 runs | v Worcestershire | Old Trafford, Manchester | 1902 | f5824 |
| 159 runs | v Kent | Old Trafford, Manchester | 1951 | f19116 |
| 154 runs | v Sussex | Old Trafford, Manchester | 1885 | f2925 |
| 154 runs | v Kent | Old Trafford, Manchester | 2000 | f45244 |
| 153 runs | v Warwickshire | Edgbaston, Birmingham | 1950 | f18683 |
| 153 runs | v Yorkshire | Headingley, Leeds | 1956 | f21289 |
| 151 runs | v Oxford University | The University Parks, Oxford | 1883 | f2618 |
| 150 runs | v Derbyshire | Queen's Park, Chesterfield | 1909 | f7822 |
| 147 runs | v Surrey | Kennington Oval, Kennington | 1887 | f3182 |
| 147 runs | v Warwickshire | Edgbaston, Birmingham | 2011 | f53219 |
| 146 runs | v Warwickshire | Trafalgar Road, Southport | 1962 | f24395 |
| 146 runs | v Hampshire | United Services Ground, Portsmouth | 1980 | f33164 |
| 145 runs | v Yorkshire | Bramall Lane, Sheffield | 1895 | f4238 |
| 141 runs | v Oxford University | Christ Church Ground, Oxford | 1906 | f6843 |
| 141 runs | v Durham | Riverside Ground, Chester-le-Street | 2000 | f45107 |
| 140 runs | v Yorkshire | Old Trafford, Manchester | 1919 | f9367 |
| 140 runs | v Sussex | Old Trafford, Manchester | 1924 | f10919 |
| 138 runs | v Glamorgan | St Helen's, Swansea | 1925 | f11232 |
| 138 runs | v Leicestershire | Aigburth, Liverpool | 1926 | f11525 |
| 138 runs | v Gloucestershire | Aigburth, Liverpool | 1926 | f11595 |
| 138 runs | v Nottinghamshire | Old Trafford, Manchester | 1978 | f32145 |
| 136 runs | v Kent | Old Trafford, Manchester | 1880 | f2293 |
| 135 runs | v Derbyshire | Old Trafford, Manchester | 1934 | f14752 |
| 135 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1946 | f17073 |
| 134 runs | v Sussex | Old Trafford, Manchester | 1956 | f21406 |
| 134 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1964 | f25285 |
| 133 runs | v Oxford University | The University Parks, Oxford | 1962 | f24228 |
| 132 runs | v Leicestershire | Old Trafford, Manchester | 1932 | f13984 |
| 131 runs | v Derbyshire | Old Trafford, Manchester | 1904 | f6495 |
| 131 runs | v Essex | Aigburth, Liverpool | 1910 | f7941 |
| 131 runs | v Northamptonshire | Town Ground, Rushden | 1963 | f24739 |
| 130 runs | v Sussex | Old Trafford, Manchester | 1947 | f17506 |
| 129 runs | v Leicestershire | Old Trafford, Manchester | 1920 | f9564 |
| 129 runs | v Derbyshire | Queen's Park, Chesterfield | 1955 | f20940 |
| 128 runs | v Derbyshire | North Road, Glossop | 1910 | f7925 |
| 128 runs | v Glamorgan | Aigburth, Liverpool | 1924 | f10821 |
| 128 runs | v Hampshire | May's Bounty, Basingstoke | 1991 | f39360 |
| 128 runs | v Durham | Riverside Ground, Chester-le-Street | 2006 | f49352 |
| 126 runs | v Northamptonshire | Town Ground, Kettering | 1926 | f11562 |
| 125 runs | v Gloucestershire | College Ground, Cheltenham | 1921 | f10061 |
| 125 runs | v Kent | Bat and Ball Ground, Gravesend | 1923 | f10524 |
| 125 runs | v Essex | Hoffman's Sports and Social Club Ground, Chelmsford | 1959 | f22942 |
| 124 runs | v Derbyshire | Trafalgar Road, Southport | 1968 | f27360 |
| 123 runs | v Surrey | The Kia Oval, Kennington | 2023 | f61615 |
| 122 runs | v Leicestershire | Grace Road, Leicester | 1960 | f23199 |
| 122 runs | v Hampshire | Trafalgar Road, Southport | 2013 | f54942 |
| 121 runs | v Warwickshire | Old Trafford, Manchester | 2010 | f52385 |
| 121 runs | v Kent | St Lawrence Ground, Canterbury | 2010 | f52538 |
| 119 runs | v Essex | County Ground, Leyton | 1903 | f6212 |
| 118 runs | v Essex | Old Trafford, Manchester | 1999 | f44466 |
| 117 runs | v Oxford University | Aigburth, Liverpool | 1887 | f3141 |
| 117 runs | v Somerset | Recreation Ground, Bath | 1954 | f20495 |
| 117 runs | v Worcestershire | Old Trafford, Manchester | 1987 | f36998 |
| 116 runs | v Gloucestershire | Aigburth, Liverpool | 1888 | f3299 |
| 115 runs | v Leicestershire | Grace Road, Leicester | 1991 | f39382 |
| 113 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1938 | f16104 |
| 112 runs | v Sussex | Old Trafford, Manchester | 1892 | f3714 |
| 111 runs | v Gloucestershire | Old Trafford, Manchester | 1935 | f15071 |
| 111 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1959 | f22806 |
| 111 runs | v Derbyshire | County Ground, Derby | 1993 | f40570 |
| 111 runs | v Hampshire | The Rose Bowl, Southampton | 2002 | f46708 |
| 109 runs | v Somerset | Old Trafford, Manchester | 1949 | f18254 |
| 109 runs | v Derbyshire | Old Trafford, Manchester | 1961 | f23741 |
| 108 runs | v Gloucestershire | Spa Ground, Gloucester | 1901 | f5603 |
| 108 runs | v Leicestershire | Aylestone Road, Leicester | 1903 | f6044 |
| 108 runs | v Nottinghamshire | Trent Bridge, Nottingham | 1926 | f11572 |
| 108 runs | v Nottinghamshire | Old Trafford, Manchester | 1965 | f25852 |
| 107 runs | v Kent | Angel Ground, Tonbridge | 1904 | f6376 |
| 107 runs | v Oxford University | The University Parks, Oxford | 1923 | f10471 |
| 107 runs | v Combined Services | Old Trafford, Manchester | 1955 | f21091 |
| 106 runs | v Surrey | Kennington Oval, Kennington | 1873 | f1765 |
| 106 runs | v Glamorgan | Old Trafford, Manchester | 1925 | f11329 |
| 104 runs | v Sussex | Old Trafford, Manchester | 1869 | f1538 |
| 104 runs | v Middlesex | Emirates Old Trafford, Manchester | 2019 | f59605 |
| 103 runs | v Derbyshire | County Ground, Derby | 1906 | f6845 |
| 103 runs | v Gloucestershire | Old Trafford, Manchester | 1934 | f14723 |
| 103 runs | v Glamorgan | St Helen's, Swansea | 1971 | f28687 |
| 102 runs | v Kent | Old Trafford, Manchester | 1937 | f15916 |
| 101 runs | v Kent | Crabble Athletic Ground, Dover | 1930 | f13289 |
| 101 runs | v Nottinghamshire | Trent Bridge, Nottingham | 1934 | f14624 |
| 99 runs | v Somerset | Clarence Park, Weston-super-Mare | 1976 | f31209 |
| 98 runs | v Essex | Old Trafford, Manchester | 1964 | f25337 |
| 98 runs | v Worcestershire | Stanley Park, Blackpool | 2011 | f53328 |
| 97 runs | v Worcestershire | Aigburth, Liverpool | 1905 | f6576 |
| 97 runs | v Oxford University | The University Parks, Oxford | 1922 | f10238 |
| 97 runs | v Derbyshire | Seedhill, Nelson | 1925 | f11381 |
| 97 runs | v Hampshire | Dean Park, Bournemouth | 1926 | f11745 |
| 97 runs | v Surrey | Old Trafford, Manchester | 1989 | f38269 |
| 96 runs | v Derbyshire | Old Trafford, Manchester | 1900 | f5291 |
| 96 runs | v Surrey | The Foster's Oval, Kennington | 1993 | f40544 |
| 95 runs | v Derbyshire | County Ground, Derby | 1876 | f1968 |
| 95 runs | v Nottinghamshire | Aigburth, Liverpool | 1920 | f9728 |
| 95 runs | v Northamptonshire | County Ground, Northampton | 1939 | f16712 |
| 95 runs | v Hampshire | Old Trafford, Manchester | 1957 | f21953 |
| 94 runs | v Middlesex | Old Trafford, Manchester | 1950 | f18847 |
| 93 runs | v Somerset | Old Trafford, Manchester | 1909 | f7847 |
| 91 runs | v Gloucestershire | County Ground, Bristol | 2015 | f56426 |
| 89 runs | v Essex | County Ground, Chelmsford | 1987 | f37191 |
| 87 runs | v Kent | St Lawrence Ground, Canterbury | 1907 | f7269 |
| 86 runs | v Combined Services | Old Trafford, Manchester | 1958 | f22331 |
| 86 runs | v Surrey | Church Road, Lytham St Annes | 1992 | f40075 |
| 85 runs | v Hampshire | United Services Ground, Portsmouth | 1925 | f11192 |
| 85 runs | v Sussex | Aigburth, Liverpool | 1964 | f25365 |
| 84 runs | v Nottinghamshire | Old Trafford, Manchester | 1899 | f5190 |
| 84 runs | v Leicestershire | Kirkby Road, Barwell | 1946 | f17160 |
| 84 runs | v Nottinghamshire | Old Trafford, Manchester | 1947 | f17704 |
| 84 runs | v Somerset | County Ground, Taunton | 1949 | f18421 |
| 83 runs | v Middlesex | Old Trafford, Manchester | 1911 | f8393 |
| 83 runs | v Derbyshire | Old Trafford, Manchester | 1952 | f19584 |
| 83 runs | v Sussex | County Ground, Hove | 1954 | f20672 |
| 82 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1950 | f18723 |
| 82 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1974 | f30153 |
| 80 runs | v Wales | Stanley Park, Blackpool | 1928 | f12525 |
| 80 runs | v Warwickshire | Old Trafford, Manchester | 1958 | f22340 |
| 79 runs | v Hampshire | Old Trafford, Manchester | 1959 | f22686 |
| 76 runs | v Surrey | Old Trafford, Manchester | 1907 | f7165 |
| 76 runs | v Worcestershire | County Ground, New Road, Worcester | 2005 | f48655 |
| 75 runs | v Kent | Angel Ground, Tonbridge | 1895 | f4263 |
| 75 runs | v Gloucestershire | Wagon Works Ground, Gloucester | 1923 | f10531 |
| 75 runs | v Kent | St Lawrence Ground, Canterbury | 2003 | f47307 |
| 74 runs | v Gloucestershire | Stanley Park, Blackpool | 1956 | f21442 |
| 74 runs | v Gloucestershire | The Royal and Sun Alliance County Ground, Bristol | 1985 | f35730 |
| 73 runs | v Derbyshire | Old Trafford, Manchester | 1878 | f2119 |
| 72 runs | v Derbyshire | Old Trafford, Manchester | 1932 | f13788 |
| 72 runs | v Warwickshire | Old Trafford, Manchester | 1955 | f20842 |
| 72 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1957 | f21830 |
| 72 runs | v Northamptonshire | County Ground, Northampton | 1979 | f32650 |
| 72 runs | v Glamorgan | St Helen's, Swansea | 1988 | f37586 |
| 71 runs | v Hampshire | County Ground, Southampton | 1899 | f5123 |
| 71 runs | v Scotland | Whitehaugh Oval, Paisley | 1956 | f21417 |
| 70 runs | v Kent | Old Trafford, Manchester | 1883 | f2621 |
| 70 runs | v Surrey | Kennington Oval, Kennington | 1904 | f6385 |
| 70 runs | v Kent | Aigburth, Liverpool | 2008 | f50964 |
| 68 runs | v Nottinghamshire | Old Trafford, Manchester | 1890 | f3562 |
| 68 runs | v Middlesex | Old Trafford, Manchester | 1893 | f3921 |
| 68 runs | v Warwickshire | Edgbaston, Birmingham | 1959 | f22918 |
| 66 runs | v Essex | Old Trafford, Manchester | 1897 | f4719 |
| 66 runs | v Gloucestershire | Old Trafford, Manchester | 1898 | f4965 |
| 66 runs | v Glamorgan | Sophia Gardens, Cardiff | 1981 | f33682 |
| 66 runs | v Worcestershire | County Ground, New Road, Worcester | 1989 | f38070 |
| 65 runs | v Derbyshire | County Ground, Derby | 1880 | f2332 |
| 65 runs | v Derbyshire | County Ground, Derby | 1898 | f4871 |
| 65 runs | v Warwickshire | Edgbaston, Birmingham | 2010 | f52439 |
| 64 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1900 | f5321 |
| 64 runs | v Sussex | County Ground, Hove | 1935 | f14950 |
| 64 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1947 | f17735 |
| 63 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1931 | f13484 |
| 63 runs | v Sussex | Old Trafford, Manchester | 1961 | f23958 |
| 62 runs | v Middlesex | Old Trafford, Manchester | 1865 | f1333 |
| 62 runs | v Derbyshire | County Ground, Derby | 1871 | f1663 |
| 62 runs | v Glamorgan | St Helen's, Swansea | 1973 | f29676 |
| 62 runs | v Warwickshire | Old Trafford, Manchester | 1989 | f38082 |
| 61 runs | v Northamptonshire | County Ground, Northampton | 1925 | f11345 |
| 60 runs | v Surrey | Kennington Oval, Kennington | 1880 | f2344 |
| 60 runs | v Nottinghamshire | Aigburth, Liverpool | 1906 | f6858 |
| 60 runs | v Kent | Old Trafford, Manchester | 1957 | f21701 |
| 60 runs | v Gloucestershire | Recreational Trust Ground, Lydney | 1966 | f26336 |
| 60 runs | v Derbyshire | County Ground, Derby | 1990 | f38701 |
| 60 runs | v Sussex | Church Road, Lytham St Annes | 1995 | f41854 |
| 60 runs | v Northamptonshire | County Ground, Northampton | 2014 | f55619 |
| 60 runs | v Durham | Stanley Park, Blackpool | 2024 | f62267 |
| 59 runs | v Marylebone Cricket Club | Lord's Cricket Ground, St John's Wood | 1878 | f2103 |
| 59 runs | v Yorkshire | Bramall Lane, Sheffield | 1899 | f5146 |
| 59 runs | v Kent | Old Trafford, Manchester | 1991 | f39390 |
| 59 runs | v Yorkshire | Headingley, Leeds | 1998 | f43831 |
| 58 runs | v Nottinghamshire | Old Trafford, Manchester | 1946 | f17175 |
| 55 runs | v Gloucestershire | College Ground, Cheltenham | 1961 | f23940 |
| 54 runs | v Derbyshire | Recreation Ground, Long Eaton | 1887 | f3160 |
| 54 runs | v Gloucestershire | Old Trafford, Manchester | 1913 | f8913 |
| 54 runs | v Sussex | Cricket Field Road, Horsham | 1983 | f34664 |
| 54 runs | v Sussex | Church Road, Lytham St Annes | 1987 | f37146 |
| 51 runs | v Nottinghamshire | Trent Bridge, Nottingham | 1988 | f37515 |
| 50 runs | v Yorkshire | Bramall Lane, Sheffield | 1881 | f2410 |
| 50 runs | v Oxford University | The University Parks, Oxford | 1885 | f2867 |