| 528 | H Verity | v Yorkshire | Melbourne Park, Kingston | 1935/36 | f15276 |
| 528 | NE Marshall | v Barbados | Sabina Park, Kingston | 1946/47 | f17451 |
| 509 | CG Butts | v Guyana | Kayman Sankar Cricket Ground, Hampton Court | 1984/85 | f35688 |
| 504 | IS Madray | v British Guiana | Bourda, Georgetown | 1956/57 | f21549 |
| 504 | RA Harper | v Guyana | Jarrett Park, Montego Bay | 1979/80 | f33005 |
| 480 | LR Gibbs | v British Guiana | Bourda, Georgetown | 1956/57 | f21549 |
| 468 | OAC Banks | v Leeward Islands | Edgar Gilbert Sporting Complex, Molyneux | 2000/01 | f45569 |
| 462 | R Howorth | v Marylebone Cricket Club | Sabina Park, Kingston | 1947/48 | f17846 |
| 462 | R Dhanraj | v Trinidad and Tobago | Sabina Park, Kingston | 1992/93 | f40417 |
| 462 | I Khan | v Trinidad and Tobago | Brian Lara Stadium, Tarouba | 2017/18 | f58219 |
| 440 | CG Butts | v Guyana | Sabina Park, Kingston | 1990/91 | f39164 |
| 438 | NE Marshall | v Trinidad | Sabina Park, Kingston | 1954/55 | f20768 |
| 438 | NC Guishard | v Leeward Islands | Sabina Park, Kingston | 1981/82 | f34009 |
| 433 | DR Parry | v Combined Leeward and Windward Islands | Queen's Park (Old), St George's | 1978/79 | f32521 |
| 432 | NE Marshall | v Barbados | Melbourne Park, Kingston | 1946/47 | f17448 |
| 430 | EAS Prasanna | v Indians | Sabina Park, Kingston | 1975/76 | f31032 |
| 426 | CG Butts | v Guyana | Sabina Park, Kingston | 1983/84 | f35047 |
| 426 | GLL Linton | v Barbados | Kensington Oval, Bridgetown | 1988/89 | f37996 |
| 420 | R Nanan | v Trinidad and Tobago | Sabina Park, Kingston | 1982/83 | f34475 |
| 420 | WD Phillip | v Leeward Islands | Chedwin Park, Spanish Town | 1996/97 | f43010 |
| 420 | MV Nagamootoo | v Guyana | Sabina Park, Kingston | 1996/97 | f43061 |
| 420 | WD Phillip | v Leeward Islands | Sabina Park, Kingston | 1999/00 | f45018 |
| 420 | OAC Banks | v Leeward Islands | Ronald Webster Park, The Valley | 2002/03 | f47108 |
| 420 | K Kantasingh | v Combined Campuses and Colleges | Sabina Park, Kingston | 2008/09 | f51522 |
| 414 | LR Gibbs | v British Guiana | Bourda, Georgetown | 1959/60 | f22960 |
| 408 | WE Bowes | v Yorkshire | Melbourne Park, Kingston | 1935/36 | f15276 |
| 408 | BBM Gaskin | v British Guiana | Bourda, Georgetown | 1952/53 | f19816 |
| 408 | MV Nagamootoo | v Guyana | Sabina Park, Kingston | 2000/01 | f45693 |
| 404 | JA Bishop | v West Indies Academy | Sabina Park, Kingston | 2023/24 | f62182 |
| 402 | GM Lee | v LH Tennyson's XI | Sabina Park, Kingston | 1927/28 | f12226 |
| 402 | BS Chandrasekhar | v Indians | Sabina Park, Kingston | 1975/76 | f31032 |
| 402 | R Nanan | v Trinidad and Tobago | Sabina Park, Kingston | 1990/91 | f39144 |
